alpha 1-Antitrypsin Deficiency

Medical Dictionary -> alpha 1-Antitrypsin Deficiency

alpha 1-Antitrypsin Deficiency


Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN, leading primarily to degradation of elastin of the alveolar walls, as well as other structural proteins of a variety of tissues. (From Scriver, Beaudet, Sly, & Valle, The Metabolic and Molecular Bases of Inherited Disease, 7th ed, p4125)


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