Thymine DNA Glycosylase

Medical Dictionary -> Thymine DNA Glycosylase

Thymine DNA Glycosylase


An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.


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