Pseudohypoaldosteronism

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Pseudohypoaldosteronism

A heterogeneous group of disorders with common symptoms of apparent HYPOALDOSTERONISM despite the elevated levels of ALDOSTERONE and RENIN. Other clinical symptoms include HYPERKALEMIA with (Type I) or without (Type II) sodium wasting. Pseudohypoaldosteronism can be the result of defective MINERALOCORTICOID RECEPTORS or defects in the epithelial SODIUM CHANNEL. It can also be acquired after KIDNEY TRANSPLANTATION.