Platelet Membrane Glycoprotein IIb

Medical Dictionary -> Platelet Membrane Glycoprotein IIb

Platelet Membrane Glycoprotein IIb


Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.


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