Phosphatidylinositol Diacylglycerol-Lyase

Medical Dictionary -> Phosphatidylinositol Diacylglycerol-Lyase

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Phosphatidylinositol Diacylglycerol-Lyase

A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a PHOSPHOLIPASE C. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.