Paraneoplastic Cerebellar Degeneration

Medical Dictionary -> Paraneoplastic Cerebellar Degeneration

Paraneoplastic Cerebellar Degeneration


Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)


© MedicalDictionaryweb.com 2012 | Contact Us | Terms of Use | Teeth Whitening | Low Carb Foods and Diets