P-Glycoprotein

Medical Dictionary -> P-Glycoprotein

P-Glycoprotein


A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).


© MedicalDictionaryweb.com 2012 | Contact Us | Terms of Use | Teeth Whitening | Low Carb Foods and Diets