Oncogene Protein pp60(v-src)

Medical Dictionary -> Oncogene Protein pp60(v-src)

Oncogene Protein pp60(v-src)


A tyrosine-specific protein kinase encoded by the v-src oncogene of Rous sarcoma virus. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine.


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