Myosin-Light-Chain Kinase

Medical Dictionary -> Myosin-Light-Chain Kinase

Myosin-Light-Chain Kinase


An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and calmodulin. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.


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