Lymphocyte Specific Protein Tyrosine Kinase p56(lck)

Medical Dictionary -> Lymphocyte Specific Protein Tyrosine Kinase p56(lck)

Lymphocyte Specific Protein Tyrosine Kinase p56(lck)


This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.


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