Interferon Regulatory Factor-3

Medical Dictionary -> Interferon Regulatory Factor-3

Interferon Regulatory Factor-3


An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.


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