Indoleamine-Pyrrole 2,3,-Dioxygenase

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Indoleamine-Pyrrole 2,3,-Dioxygenase


A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.

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