CD4-Positive T-Lymphocytes

Medical Dictionary -> CD4-Positive T-Lymphocytes

CD4-Positive T-Lymphocytes


A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.


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