Arachidonate 12-Lipoxygenase

Medical Dictionary -> Arachidonate 12-Lipoxygenase

Search:

Arachidonate 12-Lipoxygenase

An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in platelets. EC 1.13.11.31.