Activating Transcription Factors

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Activating Transcription Factors

Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact with EARLY PROMOTERS from ADENOVIRUSES. They are a family of basic leucine zipper transcription factors that bind to the consensus site TGACGTCA of the cyclic AMP response element, and are closely related to CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN.